Department of Chemistry

The Department of Chemistry carries out scientific research work through a large number of various researches and projects. Within the framework of these researches, the synthesis of new derivatives of different classes of organic compounds and the examination of their physiological activities are being done. The complete spectral characterization of these compounds involves spectroscopic and spectrometric methods, as well as crystallographic analysis of synthesized compounds, with the aim of determining the relationship between structure and physiological action in order to synthesize new more active products.

Part of the mentioned researches refers to the optimization and validation of modern tandem separation and analytical methods (GC / MS), (GC / MS / MS), (LC / MS / MS), (HPLC / MS) and their application in the determination of various substances (pesticides, metal ions, anions, drugs, newly synthesized psychoactive substances (NPSs), radionuclides, antioxidants, etc.) in complex real matrices-biological samples, pharmaceuticals, food, wine and environmental samples. Statistical analysis include correlation using PCAs and cluster analysis and modeling processes in the environment. It is examined and studied kinetics of different processes, optimization of chromatographic methods with mass and tandem mass spectrometry (GC / MS) and (GC / MS / MS) in analytical toxicology.

Also, work is underway to the development of robust and sensitive methods of different NPCs using SPE extraction and tandem chromatographic techniques with optimization of detection and determination on MS / MS. Examining the biological and phytochemical activity of active components, determination of polyphenolic profile, endemic plants from characteristic geographical areas using tandem HPLC / UV / Vis method. Determination of the macro and microelement content in herbal tea samples through optical emission spectrometry with induced coupled plasma (ICP - OES) with the aim of gaining insight into the mineral status and, therefore, the safety of medicinal plants.

Research related to the structuring of polymer nanocomposites and functional materials using different precursors through the implementation of several different phases and activities at the Department of Chemistry. The work is based on testing the properties of hybrid polymeric materials for specific applications and determining the influence of different types of fillers and additives and the effects of γ-radiation on the properties of polymer composites in order to obtain the materials of desired properties. Also, the application of suitable sensor materials and polymers with appropriate roles is investigated, either as a material for the construction of the receptor itself or a material for immobilization of the chemical type responsible for analyte recognition. These new electrode/modifier materials will be used for the simple, effective, reliable, sensitive and selective determination of bio-based and industrial compounds, drugs and pollutants in samples with as little prior sample preparation as possible. ...